5-HT3

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Introduction

5-HT3 is a serotonin receptor. 5-HT3 is not a classic cannabinoid receptor but its activity is modulated by cannabinoids. Since cannabinoids have a physiological effect on 5-HT3 it is effectively a cannabinoid receptor.

Chemical Name

5-HT3 receptor

IUPHAR entry

Wikipedia Entry

Tags

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Phytocannabinoids

THC

Endocannabinoids

Terpenes

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Literature Discussion

Anandamide Δ9THC  

Refrerences:

Pertwee, R.G., Howlett, A.C., Abood, M.E., Alexander, S.P.H., Di Marzo, V., Elphick, M.R., Greasley, P.J., Hansen, H.S., Kunos, G., Mackie, K., et al. (2010). International Union of Basic and Clinical Pharmacology. LXXIX. cannabinoid receptors and their ligands: beyond CB₁ and CB₂. Pharmacol. Rev. 62, 588–631.

Distribution Summary

5-HT3 is widely expressed throughout the central and peripheral nervous system.