8α-OH-Δ9-THC

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Introduction

8α-OH-Δ9-THC is a metabolite from THC that has also been identified recently in the cannabis plant. Its therapeutic potential remains unknown.

Chemical Name

8α-hydroxy-Δ9-THC

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Literature Discussion

8α-OH-Δ9-THC has been identified in the cannabis plant. It binds to both CB1 and CB2 (Radwan et al., 2015)

References:

Radwan, M. M., ElSohly, M. A., El-Alfy, A. T., Ahmed, S. A., Slade, D., Husni, A. S., … Ross, S. A. (2015). Isolation and Pharmacological Evaluation of Minor cannabinoids from High-Potency Cannabis sativa. Journal of natural products, 78(6), 1271-1276. https://doi.org/10.1021/acs.jnatprod.5b00065